학력

• 덕성여자대학교 식품영양학과 졸업 이학사
• 경희대학교 식품영양학과 졸업 이학석사
• 경희대학교 식품영양학과 졸업 이학박사

주요경력

• 現 을지대학교 식품영양학과 조교수
• 現 식생활문화학회 상임이사
• 現 한국식품조리과학회 평이사
• 現 서울물연구원 연구개발협의회 위촉직 위원
• 前 경희대학교 나노의약생명과학과 BK21플러스사업단 학술연구교수
• 前 경희대학교 나노의약생명과학과 BK21플러스사업단 연구박사

연구실적

• Ganoderma boninense mycelia for phytochemicals and secondary metabolites with antibacterial activity. J Microbiol. 2020
• Allomyrina dichotoma larval extract attenuates intestinal barrier disruption by altering inflammatory response and tight junction proteins in lipopolysaccharide-induced Caco-2 cells. Biochem Biophys Res Commun. 2020
• Development and application of an antibody that binds to interleukin-1β of various mammalian species for the treatment of inflammatory diseases. Biochem Biophys Res Commun. 2020
• Engineered human FcγRIIa fusion: A novel strategy to extend serum half-life of therapeutic proteins. Biotechnol Bioeng. 2020
• The effects of body mass index and body shape perceptions of South Korean adults on weight control behaviors; Correlation with quality of sleep and residence of place. Nutr Res Pract. 2020
• IL-10 Expression-Inducing Gut Bacteria Alleviate High-Fat Diet-Induced Obesity and Hyperlipidemia in Mice. J Microbiol Biotechnol. 2020
• Amelioration of colitis in mice by Leuconostoc lactis EJ-1 by M1 to M2 macrophage polarization. Microbiol Immunol. 2020
• Lactobacillus sakei S1 Improves Colitis Induced by 2,4,6-Trinitrobenzene Sulfonic Acid by the Inhibition of NF-κB Signaling in Mice. J Microbiol Biotechnol. 2020
• Upregulation of caveolin-1 and its colocalization with cytokine receptors contributes to beta cell apoptosis. Sci Rep. 2019
• Lactobacillus plantarum NK3 and Bifidobacterium longum NK49 Alleviate Bacterial Vaginosis and Osteoporosis in Mice by Suppressing NF-κB-Linked TNF-α Expression. J Med Food. 2019
• Anti-Oxidant Effects of Highly Bioavailable Curcumin Powder in High-Fat Diet Fed- and Streptozotocin-Induced Type 2 Diabetic Rats. Korean J Food Nutr. 2019
• Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 simultaneously alleviate high-fat diet-induced colitis, endotoxemia, liver steatosis, and obesity in mice. Nutr Res. 2019
• Protective effect of lycopene against cytokine-induced β-cell apoptosis in INS-1 cells. J Nutr Health. 2018
• Fermented Red Ginseng Alleviates Cyclophosphamide-Induced Immunosuppression and 2,4,6-Trinitrobenzene- sulfonic Acid-Induced Colitis in Mice by Regulating Macrophage Activation and T Cell Differentiation. Am J Chin Med. 2018
• Evidence for interplay among antibacterial-induced gut microbiota disturbance, neuro-inflammation, and anxiety in mice. Mucosal Immunol. 2018
• Simultaneous Amelioratation of Colitis and Liver Injury in Mice by Bifidobacterium longum LC67 and Lactobacillus plantarum LC27. Sci Rep. 2018
• Oral administration of Proteus mirabilis damages dopaminergic neurons and motor functions in mice. Sci Rep. 2018
• Anxiolytic-like effect of Bifidobacterium adolescentis IM38 in mice with or without immobilisation stress. Benef microbes. 2018
• Tyndallized Lactobacillus plantarum HY7712 restores whole body γ-irradiation-impaired Th cell differentiation in mice. J Microbiol Biotechnol. 2017
• Anxiolytic-like effect of Bifidobacterium adolescentis IM38 in mice with or without immobilisation stress. Benef Microbes. 2017
• Gastrointestinal inflammation by gut microbiota disturbance induces memory impairment in mice. Mucosal Immunol. 2017
• Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 Attenuate Gardnerella vaginalis-Infected Bacterial Vaginosis in Mice. Nutrients. 2017
• Lactobacillus fermentum IM12 attenuates inflammation in mice by inhibiting NF-κB-STAT3 signalling pathway. Benef Microbes. 2017
• A mixture of the probiotic strains Bifidobacterium longum CH57 and Lactobacillus brevis CH23 ameliorates colitis in mice by inhibiting macrophage activation and restoring the Th17/Treg balance. J Funct Foods. 2016
• Lactobacillus sakei K17, an inducer of IL-10 expression in antigen-presenting cells, attenuates TNBS-induced colitis in mice. Immunopharmacol Immunotoxicol. 2016
• Irisolidone attenuates ethanol-induced gastric injury in mice by inhibiting the infiltration of neutrophils. Mol Nutr Food Res. 2016
• Anti-Inflammatory and Antioxidant Mechanism of Tangeretin in Activated Microglia. J Neuroimmune Pharmacol. 2016
• Orally administrated Lactobacillus pentosus var. plantarum C29 ameliorates age-dependent colitis by inhibiting the nuclear factor-kappa B signaling pathway via the regulation of lipopolysaccharide production by gut microbiota. PloS one. 2015
• Amelioration of trinitrobenzene sulfonic acid-induced colitis in mice by liquiritigenin. J Gastroenterol Hepatol. 2015
• Lactobacillus brevis G101 inhibits the absorption of monosodium glutamate in mice. J Microbiol Biotechnol. 2014
• Doenjang, a Korean soybean paste, ameliorates TNBS-induced colitis in mice by suppressing gut microbial lipopolysaccharide production and NF-κB activation. J Funct Foods. 2014
• The Rhizome Mixture of Anemarrhena asphodeloides and Coptidis chinensis Ameliorates Acute and Chronic Colitis in Mice by Inhibiting the Binding of Lipopolysaccharide to TLR4 and IRAK1 Phosphorylation. Evid Based Complement Alternat Med. 2014
• Ursolic acid isolated from the seed of Cornus officinalis ameliorates colitis in mice by inhibiting the binding of lipopolysaccharide to Toll-like receptor 4 on macrophages. J Agric Food Chem. 2014
• Mangiferin ameliorates colitis by inhibiting IRAK1 phosphorylation in NF-κB and MAPK pathways. Eur J Pharmacol. 2014
• Lactobacillus plantarum CLP-0611 ameliorates colitis in mice by polarizing M1 to M2-like macrophages. Int Immunopharmacol. 2014
• Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a D-galactose-induced accelerated aging mouse model. Anaerobe. 2014
• Doenjang, a fermented Korean soybean paste, inhibits lipopolysaccharide production of gut microbiota in mice. J Med Food. 2014
• Anticolitic Effect of the Rhizome Mixture of Anemarrhena asphodeloides and Coptidis chinensis (AC-mix) in Mice. Biomol Ther. 2013
• Penta-O-galloyl-β-D-glucose ameliorates inflammation by inhibiting MyD88/NF-κB and MyD88/MAPK signalling pathways. Br J Pharmacol. 2013
• Nobiletin and tangeretin ameliorate scratching behavior in mice by inhibiting the action of histamine and the activation of NF-κB, AP-1 and p38. Int Immunopharmacol. 2013
• Lactobacillus brevis G-101 ameliorates colitis in mice by inhibiting NF-κB, MAPK and AKT pathways and by polarizing M1 macrophages to M2-like macrophages. J Appl Microbiol. 2013
• Lactobacillus casei HY7213 ameliorates cyclophosphamide-induced immunosuppression in mice by activating NK, cytotoxic T cells and macrophages. Immunopharmacol Immunotoxicol. 2013
• Lactobacillus plantarum HY7712 ameliorates cyclophosphamide-induced immunosuppression in mice. J Microbiol Biotechnol. 2013
• Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages. Eur J Pharmacol. 2013
• Echinocystic acid, a metabolite of lancemaside A, inhibits TNBS-induced colitis in mice. Int Immunopharmacol. 2013
• Lancemaside A isolated from Codonopsis lanceolata and its metabolite echinocystic acid ameliorate scopolamine-induced memory and learning deficits in mice. Phytomedicine. 2012
• Antibiotics attenuate anti-scratching behavioral effect of ginsenoside Re in mice. J Ethnopharmacol. 2012
• Kalopanaxsaponin B Ameliorates TNBS-Induced Colitis in Mice. Biomol Ther. 2012
• Ginsenoside Re ameliorates inflammation by inhibiting the binding of lipopolysaccharide to TLR4 on macrophages. J Agric Food Chem. 2012
• Development of fecal microbial enzyme mix for mutagenicity assay of natural products. J Microbiol Biotechnol. 2012
• The role of intestinal microflora in anti-inflammatory effect of baicalin in mice. Biomol Ther. 2012
• Inhibitory effect of Lactobacillus plantarum K-1 on passive cutaneous anaphylaxis reaction and scratching behavior in mice. Arch Pharm Res. 2011
• Metabolic activities of ginseng and its constituents, ginsenoside rb1 and rg1, by human intestinal microflora. J Ginseng Res. 2011
• Anti-scratching behavioral effect of Lactobacillus plantarum PM008 isolated from kimchi in mice. Immunopharmacol Immunotoxicol. 2011

연구분야

• 장내미생물과 면역계의 관계 규명 연구
• 염증 개선 및 치료 기능성 소재 개발 연구
• 고부가가치 기능성 프로바이오틱스 개발 연구